Spermidine: The Incredible Anti-Aging Supplement That Inhibits 9 of the 12 Hallmarks of Aging. The Best Way To Supplement Spermidine Using Primeadine with Leslie Kenny. EP 006

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This week's episode of the Stephen McCain podcast is all about the supplement Spermidine. The amazing anti-aging supplement with a terrible name. It inhibits 9 of the 12 hallmarks of aging.

If you care about aging, you cannot ignore this supplement. In this episode, I interview Leslie Kenny. She's the founder of Oxford Healthspan. They make a premiere Spermidine supplement called Primeadine.

You're going to learn why their product is the most complete Spermidine supplement on the market. And, Leslie is giving us all a 15% discount on her Primeadine Spermidine using code:  STEPHEN15.

By the end of the episode, you will know everything you need to safely and confidently supplement with Spermidine. Let's do this!

Today's Guest

Leslie Kenny

Leslie, a Southern Californian entrepreneur and graduate of Berkeley and Harvard, overcame a diagnosis of lupus and rheumatoid arthritis.

She pursued natural solutions to optimize her health and discovered spermidine, a promising compound abundant in nattō. Inspired to share its benefits, Leslie brought spermidine to the US.

At 57, she embodies the idea of aging gracefully through personal responsibility and hopes to make spermidine part of your anti-aging arsenal too.

You'll Learn

  • How spermidine was discovered.
  • Why Spermidine is a powerhouse anti-aging supplement; inhibiting 9 of the 12 Hallmarks of Aging.
  • Why food-derived spermidine is superior than synthetics, why liposomal is ineffective, and all things dosing.

If you care about anti-aging, Oxford Healthspan's Primeadine supplement is a "done for you" turnkey solution; inhibiting 9 of the 12 Hallmarks of Aging. Save 15% with code:  STEPHEN15

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Primeadine Spermidine Supplement

Spermidine inhibits 9 of the 12 Hallmarks of Aging

  1. 1
    Loss of proteostasis - As cells age, environmental stresses add up and mechanisms responsible for maintaining proper protein composition start to decline. Proteins lose their stability, autophagic processes start to fail, and misfolded proteins accumulate.
  2. 2
    Telomere Shortening - Shortened telomeres are associated with aging cells that are senescent. As cells divide, the telomere ends of chromosomes get shorter. Eventually, telomerase gets silenced and the telomeres are too short for cells to divide.
  3. 3
    Stem Cell Exhaustion - Stem cells lose their ability to divide as we age, and we are unable to replace cells that have migrated, differentiated, or died. As a result, we show outward symptoms of aging, such as gray hair.
  4. 4
    Epigenetic Alterations - Autophagy is an essential process of removing cellular waste products. It is a component of proteostasis, although now a hallmark in its own right since loss of effective autophagy is a key contributor to the decline of organelle turnover and an accelerator of aging.
  5. 5
    Mitochondrial Dysfunction - As cells age, their mitochondria start to lose their integrity due to the build-up of oxidative stress. Compromised mitochondrial function leads to a number of adverse events, such as increased apoptosis induction, that correlate with aging.
  6. 6
    Impaired Intercellular Communication - As cells age, they show an increase in self-preserving signals that result in damage elsewhere. Impaired intercellular communication with aging contributes to decline in tissue health.
  7. 7
    Impaired Autophagy - Autophagy is an essential process of removing cellular waste products. It is a component of proteostasis, although now a hallmark in its own right since loss of effective autophagy is a key contributor to the decline of organelle turnover and an accelerator of aging.
  8. 8
    Gut Dysbiosis - Microbes living in and on us are now widely understood to be intricately connected to health and disease. In part due to the gradual decline of our immune system’s effectiveness, and since one of our immune system’s roles is in shaping the diversity and species members of our microbiome, our aging microbiomes gradually lose diversity and become altered in their composition.
  9. 9
    Inflammation - “Inflammaging” is a term coined to describe the gradual increase of inflammation as we age. It has wide-ranging implications in disease-related activity such as arteriosclerosis, neuroinflammation, osteoarthritis and bone degradation. Inflammation is also clearly linked to all other hallmarks of aging both in its tendency to promote and result from other hallmarks.

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